【摘要】 对经病理证实的57例前列腺增生和19例前列腺癌患者作PSA双抗体放射免疫测定，并对其临床资料进行分析。结果显示：前列腺癌组的ISA平均水平（56．89±23．93ug/L）明显超过前列腺增生组（7．99±2．26ug/L（P＜0．01），前列腺癌阳性检出率为78．9%（15／19），对临床筛选前列腺癌具有重要意义；但由于PSA值测定时影响因素较多，前列腺增生38．6％（22／57）与早期前列腺癌有重叠现象，在分析结果时宜综合判断；此外，PSA水平对前列腺癌的临床分期也是重要参考指标。更多还原

【Abstract】 Serum Prostate Specific Antigen(PSA) assay by mean of radioimmunoassay was carried out and evaluated in 57 bening prostatic hyperplasia (BPH) and in 19 prostatic cancer(PCa)diagnosed by pathology. The mean PSA level of PCa (56.89 + 23.93ug/L) was greatlyhigher than that of BPH (7 .99 + 2.26ug/L) (P < 0.01 ).Tha sensitivity of PSA assay in the detection of PCa was 78. 9% (15/19). Itshowed that PSA assay was most significant in the differrential diagnosis of PCa. It should be noted that, because PSAassay was affected bysome factors, the PSAlevel of 38.6% of BPH(22/57) was overlapping with that of PCa, the analysis of detecd result umst be more considebole. Moreover, The PSA assay was valuable in the clinical bystages of PCa.更多还原