【摘要】 本文对68例多发性硬化（MS）活动期的病人进行脑脊液检查，结果发现患者脑脊液白细胞增高占29．4％，尤以首次发病者明显。其脑脊液细胞学（CSFC）的改变主要以转化型淋巴细胞反应为主。此外，MS三个临床类型（首次发病、缓解复发型及慢性进展型）的脑脊液细胞反应之间的差异无显著性意义。但缓解复发型和慢性进展型的浆细胞阳性率较首次发病者高（P＜0．05）。因此，观察MS病人CSFC免疫活性细胞反应的变化，对该病的诊断及病期、疗效的判断均有重要意义。更多还原

【Abstract】 The article reports the cytologic change of CSF in 68 patients with multiple sclerosis(MS) atactive stage. Finding: the number of WBC in CSF of MS patients was elevated(about 29. 4% ).The main alteration of CSF cytology in multiple sclerosis was proliferative and activated reactionof lymphocytes. Result: observation of CSF cytologic change in immune competent cell reactionwas important for diagnosis and judgement on stadium and curative effect.更多还原