【摘要】 通过３－羟基异噻唑和４－氰基－５－甲硫基－３－羟基异噻唑与芳基磺酰氯在碱性条件下缩合，合成了３－芳基磺酰氧基异噻唑和３－芳基磺酰氧基－４－氰基－５－甲硫基－异噻唑．对所合成的化合物进行了除草活性的测定．更多还原

【Abstract】 To look for novel compounds with biological activity, 3 arylsulfonyloxy(substituted) isothiazoles were synthesized by the condensation of 3 hydroxy(substituted) isothiazoles with arylsulfonylchlorides in the presence of base. The strctures of target compounds were confirmed by elemental analysis, 1H NMR, IR, MS. Also, the single crystal structures of compounds 3c and 4b were determined. All the facts ascertained that the sulfonylization position was oxygen atom of isothiazole heterocycle. The herbicidal activities of title compounds were determined and the result showed that it was possible that they were ALS inhibitors.更多还原