【摘要】 发现院内深部真菌感染73例(91例次),占同期院内感染8.7％。应用病例-对照研究,单因素分析发现:9项因素与真菌感染有关,包括患者年龄、基础疾病、住院天数和次数、原有其它院内感染、抗菌药物使用种类及天数、留置导尿、恶性肿瘤等。住院天数和次数、抗生素使用天数和种类、基础疾病的严重程度等多水平因素与真菌感染有明显量-效关系。logstic回归多因素分析结果表明:多种抗菌药物的使用、原有其它院内感染(医源性因素)、60岁以上老人及1岁以内的婴幼儿、致死性疾病(宿主因素)是最主要危险因素。更多还原

【Abstract】 8.7% of all hospital - acquired infections were caused by fungi, In the univariate analysis, nine risk factors were related to nosocomial fungal infections including ages, underlying distases, frequence and duration of hospitaliza-tion,antibiotic treatment,urine catheter and malignment diseases by a matched case- control analysis.Logistic regression analysis showed the major risk factors were: 1. Treatment of three or more antidiotics. 2. Prior hospital - acquired infections . 3. Older over 65 year - old or infant in 1 year - old. 4. Fatal underlying disease.更多还原