【摘要】 目的探讨硫酸软骨素对软骨细胞增殖影响的作用机制及其在耳硬化症防治上的应用前景。方法用硝基四氮唑蓝法研究硫酸软骨素对体外培养兔软骨细胞琥珀酸脱氢酶（ＳＤＨ）活性的影响。结果对照组与实验组ＳＤＨ活性无明显差异，即加入或不加入硫酸软骨素的兔软骨培养细胞内ＳＤＨ活性无明显改变（Ｐ＞０．０５）。结论硫酸软骨素有望用于治疗耳硬化症更多还原

【Abstract】 bjective To figure out the mechanism of chondroitin sulfate on the proliferation of chondrocytes and the possible role chondroitin sulfate may play in treating otosclerosis. Methods The effect of chondroitin sulfate on the succinate dihydrogenase(SDH) of chondrocytes were measured by nitroblue tetrazolium method. Results No difference was demonstrazed between the activity of SDH on control group and experiment group(P< 0.05 ).\ So the activity of SDH was unaffected by chondroitin sulfate. Conclusion Chondroitin sulfate may be used in treatment of otosclerosis.更多还原