【摘要】 在心衰常规治疗基础上，对６１例扩张型心肌病（ＤＣＭ）患者随机加用地尔硫艹卓（３０ｍｇｂｉｄ）或安慰剂治疗，平均疗程８．５月。结果：对照组（ｎ＝３０）ＬＶＥＤｄ明显增大和ＬＶＥＦ值显著降低；治疗组中ＬＶＥＤｄ＜７０ｍｍ组患者ＬＶＥＤｄ明显缩小和ＬＶＥＦ明显增加，治疗前后比较均有显著性差异（Ｐ＜０．０５），病人生活质量明显提高。提示加用地尔硫艹卓治疗ＤＣＭ，通过保护心肌，使患者左室功能改善，是ＤＣＭ早期治疗的有效方法之一。更多还原

【Abstract】 n the study,diltiazem (30mg two times daily) or placebo were given to 61 patients with dilated cardiomyopathy (DCM) in addition to conventional therapy of heart failure by random dividing groups,at a mean follow-up period of 8.5 months.The results showed that left ventricular end-diastolic diameter (LVEDd) increased and LVEF reduced markedly (P<005),and life quality improved obviously in diltiazem group.The study suggests that adjunctive diltiazem treatment in DCM might improve ventricular function and protect myocardium,that is one of the effective methods of early phase therapy in DCM.更多还原