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人参二醇组皂甙的诱变作用研究
Study on the mutagenic effect of panaxadiol saponin
【摘要】 目的:观察人参二醇组皂甙对小鼠体细胞及生殖细胞遗传物质的损伤作用。方法:采用小鼠骨髓嗜多染红细胞MNT及小鼠精子畸形试验。结果:二醇组皂甙不能诱发微核频率和精子畸形频率增高(P>0.05)。结论:人参二醇组皂甙无诱变活性。
【Abstract】 Objective:Observation on the genetic damage effect of panaxadiol saponia (PDS) on mouse somatic cell and germ cell. Methods:Abnormal sperm test of mouse and the mironucleus test of mouse bone marorow cell (MNT) were used. Results:PDS itself could not increase sperm aberration and MN frequencies;the difference was not remarkable (P>0. 05). Conclusion: These results indicated that panaxadiol saponia had not themutation effect.
【关键词】 人参二醇组甙;
微核;
精子畸形;
诱变性;
【Key words】 panaxadiol saponia; micronuleus; sperm aberration; mutagenicity;
【Key words】 panaxadiol saponia; micronuleus; sperm aberration; mutagenicity;
- 【文献出处】 白求恩医科大学学报 ,JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE , 编辑部邮箱 ,1998年06期
- 【分类号】R285
- 【被引频次】8
- 【下载频次】37