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胆汁酸测定在梗阻性黄疸及肝硬化中的应用

The application of bile acid test in patients with obstructive jaundice and liver cirruhosis

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【作者】 贾玫钟京梅荣嵘王春燕赵捷

【Author】 Jia Mad; Zhong Jingmei; Rong Rong, et al(The People’s Hospital Affilited To Beijing Medical University, Beijing 100044)

【机构】 北京医科大学人民医院检验科!100044中华医学会北京分会北京医科大学人民医院检验科!100044

【摘要】 为了探讨梗阻性黄疸手术前后血清总胆汁酸(TBA)的意义和肝硬化患者血清中TBA的浓度,我们分别测定了30例梗阻性黄疽患者及30例肝硬化患者血清中TBA浓度。结果:在梗阻性黄殖患者实施外科手术后第四天血清中TBA浓度即恢复正常。肝硬化患者血清中TBA浓度明显增高,为110.4±106.2μmol/L(正常值0~10μmol/L)。而ALT升高不明显,为37.6±19.9U/L(正常值5~35U/L)。提示TBA测定是梗阻性黄疸患者手术后痊愈过程中最灵敏的生化指标,同时也是肝硬化患者较为敏感的指标。

【Abstract】 To discuss the importance of serum total bile acid (TBA) before and after patients operated for obstructive jaundice and TBA concentration in the serum of liver cirruhosis patient.Method: The serum TBA concentration of 30 obstructive jaundice patients and 30 liver cirruhosis patients were exmined. Result: TBA concentration in the serum of obstructive jaundice patients restoresto normal four days, postoperative TBA concentration in serum of liver cirruhosis patients showed remarkable increase but the increase of ALT was not obvious. Conclusion: It indicates that TBA is themost sensitive biochemical index in the course of recovery after aperation for obstructive jaundice patients as well as a sensitive index for liver cirruhosis patients.

【关键词】 胆汁酸梗阻性黄疸肝硬化
【Key words】 Bile acidObstructive jaundiceCirruhosis of liver
  • 【文献出处】 北京医学 ,Beijing Medical Journal , 编辑部邮箱 ,1998年05期
  • 【分类号】R446.11
  • 【被引频次】5
  • 【下载频次】41
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