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西沙必利对功能性消化不良患者胃电的影响

Effect of cisapride on gastric myoelectrical activity in functional dyspepsia

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【作者】 王启之吴鸿悌徐希岳李克力张长玲

【Author】 Wang Qizhi,Wu Hongti,Xu Xiyue,Li Keli,Zhang Changling (Department of Internal Medicine,Affliated Hospital of Bengbu Medical College,Anhui 233004 )

【机构】 蚌埠医学院附属医院消化科

【摘要】 目的:探讨功能性消化不良(FD)患者胃电改变及西沙必利对胃电的影响。方法:对38例FD患者进行空腹及服西沙必利后60min体表胃电图(EGG)描记。结果:FD患者胃电节律紊乱发生在胃体部为42.11%,胃窦部为63.16%;服西沙必利后60min胃体电节律紊乱50%好转,胃窦部58.33%消失。结论:胃动力障碍是FD的主要原因,胃动力药西沙必利能使胃电节律紊乱好转;对FD患者可提倡进行EGG检查,以指导临床治疗。

【Abstract】 Objective:To study the effect of cisapride on gastric myoelectrical activity in the patients with functional dyspepsia.Methods:Cutaneous electrogastrograms were record in 38 cases with functional dyspepsia in empty stomach before and 60 minutes after cisaprid treatment.Results:The gastric myoelectrical dysrhythmia was found in 42.11% of the cases in the gastric body and in 63.16% in the gastric antrum of functional dyspepsia.Dysrhythmia in gastric body was ameliorated in 50% of the cases and in the gastric antrum was disappeared in 58.33% of the cases under cisapride treatment.Conclusions:Gastric dysmotility was the main cause of functional dyspepsia.Cisapride is effective in treatment of functional dyspepsia due to dysmotility.Cutaneous electrogastrogram can be used in guiding the treatment of functional dyspepsia.

【关键词】 消化不良西沙必利胃电描记术
【Key words】 dyspepsiaelectrogastrogramcisapride
  • 【文献出处】 蚌埠医学院学报 ,JOURNAL OF BENGBU MEDICINAE COLLEGE , 编辑部邮箱 ,1998年05期
  • 【分类号】R573
  • 【被引频次】6
  • 【下载频次】17
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