【摘要】 采用钾离子透入测痛法和脑脊液推挽灌流法,观察轻重不同推拿手法对家兔痛阈的影响及兔中央灰质区β-内啡肽含量的变化。结果可见:轻重手法均能提高家兔痛阈,并且轻手法镇痛时中央灰质区灌流液中β-内啡肽含量增加,而重手法作用后,内啡肽含量反而减少,各变化值与对照组比较均有显著性差异(P<0.01)。说明轻重手法镇痛的作用机制存在差异,轻手法可通过激活内啡肽系统起作用。更多还原

【Abstract】 With the method of“potassium iontophoretic dolorimetry”and“push-pull perfusion of cerebrospinal fluid”,the effect of the rabbits pain threshold by soft and forcefull manipulation and the change of β-endorphin content in push-pull perfusion of peri- aqueductal gray cerebrospinal fluid were observed.The results were as the following:both soft and forcefull manipulation could raise the rabbit’s pain threshold,Moreover,the content of β-endorphin was increased while using soft manipulation and de- creased while using forcefull manipulation.Comparing with the control group,the difference was significant (P<0.01).This showed the anagelsia mechanism of soft and foreefull manipulation are different.The soft manipulation might get the effects through endorphin system.更多还原