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小柴胡汤抗尿道致病性大肠杆菌感染作用的初步观察

A Preliminary Observation on Effects of Xiaochaihu Decoction on Uropathogenic E. Coli

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【作者】 顾本清; 杨家民; 赵益业; 张其兰;

【Author】 GU Ben-qing; YANG Jia-min; ZHAO Yi-ye, et al(Shandong University of TCM, Jinan (250014))

【机构】 山东中医药大学;

【摘要】 目的:观察小柴胡汤对尿道致病性大肠杆菌(uropathogenicE.coli,UEC)增殖作用和它对人类尿道上皮细胞粘附效应的影响;方法:采用体外抑菌试验和UEC尿道上皮细胞粘附试验;结果:小柴胡汤对大肠杆菌的增殖及UEC对尿道上皮的粘附效应均有抑制作用;结论:小柴胡汤可能有抗泌尿系统感染的效应。

【Abstract】 Objective: To study the effects of Xiaochaihu Decoction(XCHD)on uropathogenic E. coli(UEC). Methods: In vitro bacterial inhibition test and in vitro adhesion of UEC to human uro-epithelial cell assay were used to investigate the anti-infectionary effects of XCHD. Results: Proliferation inhibitory effect of E. Coli treated with XCHD, and a significant reduction in number of UEC to human uro-epithelial cells was observed in the XCHD treated group at a non-inhibitory concentration of the medication in comparison with the control groups. Conclusion: It is possible that XCHD could act against urinary infection.

  • 【文献出处】 中国中西医结合杂志 ,Chinese Journal of Integrated Traditional and Western Medicine , 编辑部邮箱 ,1997年10期
  • 【分类号】R277.5
  • 【被引频次】16
  • 【下载频次】122
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