【摘要】 6只家兔右侧胫股骨中段骨膜下各注射金葡液0.67ml，而左侧同部位注射生理盐水作为对照组。取8只家兔做成双桡骨中段骨缺损4～smm，切口愈合后，右侧经皮注射金葡液0.5ml，左侧注射生理盐水作为对照组。于4、6周后处死家兔进行组织学检查。金葡液侧可见骨膜增厚，血管增殖及骨膜下新骨形成，生理盐水倒不明显。金葡液能促进骨痂形成，血管形成增多，骨痂及疤痕明显多于对照侧，有促进骨缺损的修复作用。本研究结果显示，经皮注射金葡液可能对骨折和骨不连有积极的治疗作用。更多还原

【Abstract】 0. 5 ml of Staphylococcin Aureus injection (SAI) was injected into the right middle-tibial subperiosteal tissue in 6 rabbits ; the same amount of nor-mal saline was injected into the left same tissue of the same animals as the control. BiIateral middle-radial defects of 4- 5 mm were made in other8 rabbits. After the wound healing, 0. 5 ml of SAI was percutaneously injected into the right side and the same amount of normal saline into theleft side as the control. Four and six weeks Iater, the animals were killed and examined histologically. In the six rabbits, periosteal thickening,vascular hyperplasia, and subperiosteal new bone proliferation were found on SAI side, but on the control side, the same conditions were unclear.In the eight rabbits, the callus, blood vessels and scars on SAI side were much more than the control side, indicating that SAI functions to pro-mote the formation of callus and blood vessels and the repair of osseous defects. The results of the study suggested that percutaneously injectingSAI could offer active therapeutic effects for fracture and nonunion.更多还原