【摘要】 SAV联合化疗药物喜树碱、阿糖胞苷治疗S180瘤小鼠的实验中，对每种药物分设3种剂量，并分别通过肌肉、腹腔、皮下3种途径给药，观察60d内的小鼠平均存活时间。结果表明，SAV与化疗药物联合应用的效果最佳，小鼠平均存活期达57Experimentlstudyonthetherapeuticeffectivenessontumor活期为49.29±8.08d，仅用阿糖胞苷时，小鼠平均存活期为50.2±8.06d。本实验采用了析因试验统计，表明用析因试验统计具有获得较多的信息和节约动物等优点。更多还原

【Abstract】 On the basic of certain immunologic effectiveness of SPA on cancer and tumor,we studied the possibilty of therapeutic effectiveness on tumor by combining the Staphylococcus aureus vaccine (SAV) in which the A protein is rich with chemical drugs.The average survival period of the mice with S180 tumor was observed in 60 days after treating the animals by intra-muscular,subcutaneous or intra abdominal injection with SAV,cytarabine and camptothecine alone or two of them or all of them togather in 3 doses of each drug. The results suggest that the therapeutic effectiveness by using jointly SAV and other two chemical drugs is the best in comparasion with that by using camptothecine or cytarabine alone. The average suriyal period after the different treatment mentioned above are 57 ± 2. 9, 49±8. 08 and 50. 2± 8. 06 respectively.更多还原