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醒脑健神胶囊对实验性脑血肿诱发大鼠脑水肿的作用

Effects of Xingnao Jianshen Capsule on Rats of Cerebral Edema Induced by Experimental Cerebral Hematoma

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【作者】 李克玲; 黄启福; 张丽萍; 严京; 成立华;

【Author】 Li Keling; Huang Qifu; Zhang Liping;et al.(Beijing University of Traditional Chinese Medicine)

【机构】 北京中医药大学!北京100029;

【摘要】 本实验利用大鼠脑血肿模型,观察了醒脑健神胶囊对脑血肿大鼠6、12、24、48、72小时时脑系数、脑血管通透性、脑组织含水量及钠、钾、钙、镁离子的影响。结果表明:大鼠造模后脑系数、脑血管通透性、脑组织含水量及钠离子含量随着时间推移而进行性升高,尤以造模侧为著。用醒脑健神胶囊后,能明显改善脑水肿病情,脑系数、造模侧脑组织含水量、钠离子含量及脑血管通透性的变化均比病理组减轻。

【Abstract】 The effects of Xingnao Jianshen capsule on brain coeffi-cient. cerebrovascular permeability, water content and Na+ 、K+、Ca+ +、Mg + + contents of brain tissue were observed in ratmodel of cerebral hematoma at 6、 12、 24、48、 72 hours after ad-ministration. The results showed that after modelling. braincoetticient, cerebrovascular permeability , water and Na + con-tents of the brain tissue had been increased with the lapse oftime. especially in the modelled side. Xingnao Jianshen capsulesignificantly improved cerebral edema and decreased thechanges of above indexes.

【基金】 国家“八五”攻关科研基金
  • 【分类号】R285.5
  • 【被引频次】17
  • 【下载频次】35
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