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施贝生(SPES)减轻癌痛的前期临床研究

CLINICAL STUDY OF SPES FOR THE ALLEVIATING OF CANCER PAIN

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【作者】 李集慧田常炎王绪辉郝凤庭薛启勋

【Author】 LI Ji-Hui; TIAN Chang-Yan;WANG Xu-Hui; HAO Feng-Ting; XUE Qi-Xun (Department of Anesthesiology, The 404th Hospital of PLA, Weihai, Shandong, China 264200)(Shu-Guang Hospital, Chinese Traditional Medical University of Shanghai)

【机构】 解放军第404医院!山东威海264200上海中医药大学附属曙光医院

【摘要】 30例中、晚期癌症病人均有较长时间的剧烈疼痛症状,并已用过各类镇痛药。观察期间用视觉摸拟评分法记录服用SPES24h内的镇痛作用、用药24h后的疼痛情况及其毒副作用。结果口服SPES0.9g的病人在24h内止痛作用优于其他镇痛药,VAS计分平均降至4分以下,无明显毒副作用。SPES为纯中草药制剂,使用简便,安全,可作为减轻癌痛的主要药物之一。

【Abstract】 SPES(SHI BEI SHENG; 施贝生) is provided by the International Medical Research-Botanic Lab of USA, which is an alkaloid and glycoside extracted from 15 Chinese herbs. 30 cases of middle or late phases cancer patients were selected who had severe pain for a long time and various analgesics were used without significant effects.The analgesic actlon induced by the administration of SPES was measured by visual analog scale(VAS) and its side or toxic effects were recorded. The results showed that the analgesic effect within 24 hours in patients who had taken 0.9g SPES orally was better than that of any other analgesic, with the average VAS scale lower than 4, and without any side effect. SPES is a pure Chinese herbal preparation, easy and convenient for administration, well tolerated and safe, therefore can be used as one of the chief drugs for alleviating cancer pain.

【关键词】 SPES癌痛VAS评分
【Key words】 SPESCancer painVAS
  • 【文献出处】 中国疼痛医学杂志 ,CHINESE JOURNAL OF PAIN MEDICINE , 编辑部邮箱 ,1997年04期
  • 【分类号】R730.5
  • 【被引频次】2
  • 【下载频次】47
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