【摘要】 为进一步探讨内窥镜检查对鼻咽疾患的早期诊断价值，作者应用接触式显微内窥镜配以高清晰度电视摄像系统，结合活体染色，直接动态观察２２０例鼻咽正常或不同病变受检者鼻咽粘膜上皮的微观形态。接触式显微内窥镜最大放大倍数１５０倍，连接长焦摄像镜头后图像可放大４００倍，能较清晰地显示粘膜上皮表层原位细胞的形态结构及分布排列情况，还能对粘膜毛细血管的形态及血细胞流动情况进行观察。初步观察结果显示：正常鼻咽粘膜上皮细胞排列较规则，多为柱状上皮细胞；鼻咽炎症的粘膜上皮细胞排列多不规则，脱落细胞较多，血管扩张，常见有鳞状细胞化生；鼻咽癌病灶染色不均，表层细胞形态及排列极不规则，微血管扩张、曲张，易出血。更多还原

【Abstract】 By means of contact microendoscopy and high resolution video camera system, the epithelium of nasopharyngeal mucosa, previously stained with methylene blue, were observed in vital and situ. The maximal magnification of the microendoscope is 150 times, and while connected with a long focus lens CCD camera, a 400 times video image was obtained. The shape, construction, mapping and arrangement of the mucosal superficial layers epithelium cells were observed clearly, as well as the distribution pattern of mucosal blood capillaries and the dynamic movement of blood cells were accessed directly by this technique. The primary observation results showed that: most of the epithelium of nasopharyngeal mucosa in normal subjects are ciliated epithelium, and arranged more regularly; the epithelium of nasopharygitis had an irregular distribution, vascular dilation, and had some more transition epithelium and squamous epithelium; the superficial layers on the NPC focus and the tumor nearby area have irregular staining, abnormal cellular contour, irregular distribution, vascular dilation, varix and bleeding easily.更多还原