【摘要】 本文用GC／MS方法建立了人尿中类固醇类药物美保龙（Mibolerone）及其代谢产物的监测方法，根据甾体在人体内代谢的一般规律和对质谱图的分析，在受试者的尿液中，确认检出美保龙原形和六种代谢产物，并测定了它们的代谢消除曲线。更多还原

【Abstract】 A GC/MS procedure described in this paper was applied to study the metabolism ofmibolerone in human urine Mibolerone and its six metabolites were detected in the excretion study urine. All detected metabolites of mibolerone were confirmed structurallyfirst time. The excretion curve showed that in urine mibolerone was excreted mainly asparent form I and 5β-4H metabolite Ⅵ in cunjugation.更多还原