【摘要】 测定３６例绝经后女性冠心病病人和２４例对照者的血清雌二醇（Ｅ２）、睾酮（Ｔ）、总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、高密度脂蛋白胆固醇（ＨＤＬ－Ｃ）、低密度脂蛋白胆固醇（ＬＤＬ－Ｃ）、载脂蛋白ＡⅠ（ＡｐｏＡⅠ）、载脂蛋白Ｂ１００（ＡｐｏＢ１００）水平。结果显示：ＣＨＤ组Ｅ２、ＨＤＬ－Ｃ、ＡｐｏＡⅠ显著低于对照组。ＴＣ、ＴＧ、ＬＤＬ－Ｃ、ＡｐｏＢ１００显著高于对照组。Ｅ２和Ｔ与ＡｐｏＡⅠ呈显著正相关。表明绝经后女性ＣＨＤ存在性激素环境失衡，Ｅ２水平不足，引起血脂、脂蛋白代谢紊乱，支持Ｅ２对女性ＣＨＤ有直接保护作用。更多还原

【Abstract】 The effects of sex hormone(SH) on menopausal women with coronary heart disease(CHD) were studied. The serum levels of 36 cases of menopausal women with CHD were compared with 24 cases of the control group, including levels of estradiol(E 2), tostostorone(T), total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL C), low density lipoprotein cholesterol(LDL C), apolipoprotein A 1(ApoA 1) and apolipoprotein B 100 (ApoB 100 ).The results show that serum E 2, HDL C and ApoB 100 levels are obviously higher. E 2 and T are positive related significantly to ApoA 1. All of this indicate that menopausal women with CHD lose their SH balance with the balance with the shortage of E 2 and caused lipid and lipoprotein metabolism disorders. It is suggested that E 2 can directly protect the CHD female.更多还原