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川芎嗪和推拿对椎动脉型颈椎病患者血浆血栓素B2和6-酮-前列腺素F1a的影响

Effect of Ligustrazine Hydrochloride and Massage on the Plasma Levels or TxB2 and 6-K-PGF1a in Patients with Cervical Spondylotic Vertebral Arteriopathy

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【作者】 朱珊珊汪军民夏军龙江萍喻传兵

【Author】 Zhu shanshan; Wang Junmin; Xa Jun; et al (Deparment of Rehabilitation Medicine, The First Hospital,Hubei Medical University, Wuhan 430060 )

【机构】 湖北医科大学附属第一医院康复科!武汉430060

【摘要】 比较10例健康人和10例椎动脉型颈椎病患者血浆血栓素(TxB2)、6-酮-前列腺素F1a(6-K-PGF1a)的水平,同时观察川芎嗪和推拿对这2个指标的影响。结果表明椎动脉型颈椎病患者较健康人血浆TxB2明显升高(P<0.01),川芎嗪和推拿治疗后TxB2明显下降(P<0.01)。患者和健康人的6-K-PGF1a水平并无差异(P>0.05)。提示TxB2可能在椎动脉型颈椎病的发病中有重要作用。川芎嗪和推拿可明显降低患者TxB2水平。

【Abstract】 Ten patients with cervical spondylotic vertebral arteriopathy were treated with ligustrazine hydrochloride and massage. The plasma levels of TxB2 and 6-K-PGF1a were determined by RIA before and 7 days after the treatmdnt. The results showed the plasma level of TxB2 in the patients before the treatment was significantly higher than that of normal group (P<0.01), but decreased significanthy after the treatment (P<0.05). No obvious difference was found in the plasma level of 6-K-PGF1a between the patients and normal controls (P>0.05). It was suggested that TxB2 could be an important factor in cervical spondylotic vertebral arteriopathy.

  • 【文献出处】 中国康复 ,CHINESE JOURNAL OF REHABILITATION , 编辑部邮箱 ,1997年03期
  • 【分类号】R274
  • 【被引频次】11
  • 【下载频次】48
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