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盐藻提取物对荷瘤小鼠的抑肿瘤作用
Inhibitory Effect of Extracts from Dunaliella Salina (EDS) on Cancerous Rat
【摘要】 盐藻提取物(EDS)是海洋甲藻类中提取的一种脂溶性混合物,含有大量胡萝卜素(以卜胡萝卜素为主),还有维生素E及多种不饱和脂肪酸。本实验用荷瘤小鼠(S37)灌胃EDS一个月后,观察对小鼠死亡率及肿瘤抑制率的影响。共做两批,结果相似。高剂量组肿瘤抑制率为10.97%,11.7%,低剂量组为12.53%,18.5%,均比阳性对照药β-胡萝卜素高,但不及阳性对服药环磷酰胺。灌生理盐水组小鼠死亡率为10%,灌EDS组则无死亡。
【Abstract】 Extracts from Dunaliella Salina (EDS) is a kind of fat-soluble mixture extraced from the allopelagic dunaliella salina. It contains vitamin E and unsaturated fatty acid besides large quantity of carotenoid. We observed the effect on death rate and inhibition rate to cancerous (S37) rats with EDS therapy for one month.The results of two batches were similar:the inhibition rate in the group of high dosage was 10.97%, 11.7% and in the group of low dosage was 12.53%, 18.5 %, Both the inhibition rates were better than that in group BC (Beta-carotene), but were lower than that in Cyclophosphamide group. The death rate was 10% in group of blank control and none of the EDS group was dead.
- 【文献出处】 肿瘤防治研究 ,CANCER RESEARCH ON PREVENTION AND TREATMENT , 编辑部邮箱 ,1997年01期
- 【分类号】R285
- 【被引频次】3
- 【下载频次】73