【摘要】 探讨糖化血红蛋白（HbA1c）和糖化血浆蛋白（GPP）对糖尿病的诊断价值。测定46名糖尿病患者和35名健康正常人，实验结果表明糖尿病患者HbA1C和GPP均显著高于正常人．懂尿病患者队AbA1c和GPP均与空腹血糖值呈正相关，高血糖增加了蛋白质精化作用。在临床上HbA1c和GPP可作为糖尿病患者血糖控制的一个指标，严格控制血糖对于预防或延缓糖尿病并发病极为重要。更多还原

【Abstract】 To investigate clinical value of determination of glycosylated Hemoglobin (HbA.c) and gl-ycosylated plasma protein (GPP) in tbe diagnosis of diabtes mellitus,we studied 46 patients withdiabetes mellitus (42 NIDDM, 4 IDDM) based on WHO criterion and 35 healthy control subjects were al-so studied for comparison. Tbe results showed that HbA1c and GPP iu diabetes mellitus were signifi-cantly higber than those in control subjects. Hyperglycemia euhanced protein glycation. HbA1c andGPP had significantly positive correlatin with fasting blood glucose level. The result suggestedthat strict glycaemic control was important for the prevention or delay of long-term complicationsof diabetes mellitus. The HbA1c and GPP level is as an useful index of glucose control in diabetesmellitus.更多还原