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10例原发性宫颈淋巴瘤临床分析

Ten case report on primary cervical lymphoma

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【作者】 孙敏曹军宁张国玲洪小南

【Author】 Sun Min, Cao Junning, Zhang Guoling, et al. Department of Gynecological Oncology, Cancer Hospital, Shanghai Medical University, Shanghai 200032

【机构】 上海医科大学附属肿瘤医院妇科

【摘要】 目的探讨宫颈淋巴瘤的发病、诊断、治疗及预后。方法临床资料回顾性分析。结果本组病例占同期宫颈恶性肿瘤的0.9%,10例患者平均年龄43.6岁,7例有癌肿家族史,临床症状以阴道出血和/或白带增多为主,肿瘤形态为息肉型(4例)、糜烂型(4例)和结节型(2例)。按FIGO分期:Ⅰb期8例,Ⅱb期1例,Ⅳ期1例。本组病例均经病理确诊,病理类型上属非霍奇金淋巴瘤(NHL),B细胞性,其中弥漫型裂细胞性3例,裂-无裂细胞性4例。10例患者采用手术和化疗为主的综合治疗,随访期3~66个月,除1例术后41个月腋下转移外,9例无瘤生存。结论如果发现早,治疗适当,宫颈淋巴瘤疗效并非很差。

【Abstract】 Objective and Methods Clinical feature, treatment and prognosis of primary cervical lymphoma: are retrospectively analysied. Results The disease is rare, comprising about 0.9% of all primary cervical malignancies. The average age was 43.6 years. Seven cases had history of familial carcinoma. The complaints: abnormal vaginal bleeding and/or vaginal discharge. The usual pattern of growth was endophytic or polypoid. By FIGO cervical cancer, staging system, there were 8/10 stage Ⅰb, 1/10 stage Ⅱb and 1/10 stage Ⅳ. Histologically all were NHL, B cell lesions(7/10) were the diffuse, cleaved or cleaved noncleaved cell type. Combination of surgery and chemotherapy were used for 9 of these 10 patients. The follow up period was 3 66 months. Only one patient had relapse 41 months after the treatment while, others (9/10) survived with no evidence of the disaese. Conclusion The prognosis is favorable if cervical lymphoma is discovered early and treated properly.

【关键词】 宫颈肿瘤淋巴瘤
【Key words】 Cervical neoplasms Lymphoma
  • 【文献出处】 中华肿瘤杂志 ,CHINESE JOURNAL OF ONCOLOGY , 编辑部邮箱 ,1997年03期
  • 【分类号】R737.33
  • 【被引频次】24
  • 【下载频次】151
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