【摘要】 目的：进一步认识慢性淋巴细胞白血病（ＣＬＬ）的临床及生物学特征。方法：利用形态学、免疫学及分子遗传学检测指标分析２０例ＣＬＬ患者。结果：２０例ＣＬＬ患者中Ｔ－ＣＬＬ４例（Ｔ－大颗粒淋巴细胞白血病及ＮＫ－大颗粒淋巴细胞白血病各１例，Ｔ－ＣＬＬ／淋巴瘤２例）；Ｂ－淋巴细胞白血病１６例（Ｂ－ＣＬＬ１２例，幼稚淋巴细胞白血病１例、白血病／淋巴瘤２例、白血性淋巴浆细胞性淋巴瘤１例）。结论：形态学、免疫学及分子遗传学的诊断将对慢性淋巴细胞增殖性疾病有进一步的认识。更多还原

【Abstract】 Objective:To further define the chronic lymphoid leukemia (CLL).Methods: Tweenty cases of CLL classified after the FAB proposals(1989) were retrospectively analyzed.Results:Based on the clinical features,cell/tissue morphology,immunophenotype, IgH and TCR γ gene rearrangement serum or urine immunoglobulin levels, 16 cases of B lymphoid leukemia(12 of CLL, 1 of PLL ,2 of leukemia/lymphoma, and 1 of WM) as well as 4 cases of T lymphoid leukemia(2 of leukemia/lymphoma,1 of T LGLL ,and 1 of NK LGLL) were identified.The diagnostic criteria,cell morphology,biological characteristics and prognosis for CLL were discussed.Conclusion:T leukemia/lymphoma should be incorporated in the classification of CLL.更多还原