【摘要】 采用李15～17天的Wistar大鼠胎脑新皮质组织移植到同种幼鼠大脑新皮质的相应区。分别手术后7、15、30、60、150天应用免疫组织化学和辣报过氧化物酶（HRP）追踪观察移植物存活、生长分化及其与宿土脑的整合和神经纤维联系的相关性。结果表明，大部分移植物内的幼稚神经兀不仅能存活，且能生长分化直至成熟，其形态结构和宿上脑神经允相似，移植物和宿主脑界面建立不同程度的整合，部分存活的移植物和宿上脑间形成纤维径路联系。更多还原

【Abstract】 The fetal neocortical transplant (E15~17 days of gestation) of Wistar rats was grafted to the corresponding neocortical region of young rats of same strain. The immunohistochemical study and horseradish peroxidase (HRP) retrograde trpcing were performed on the 7th,15th, 30th, 60th, 150th day after transplantation. The results showed that most grafted neuronssurvived, grew, differentiated and matured. The morphology of neurons was similar to the structure of the neocortical neurons of host brain; integration of varying degree at the interface and reciprocal connection between graft and host brain tissue were established.更多还原