【摘要】 合成了５个３－烷氧羰基甲基硫甲基头孢菌素衍生物。初步药理试验表明，化合物１对革兰氏阳性球菌有较强的抑制作用，ＭＩＣ为０．１～６．２μｇ／ｍｌ更多还原

【Abstract】 Five 3 alkoxycarbonylmethylthiomethyl cephalosporin derivatives were synthesized.Among them compound 1 a～e showed good in vitro antibacterial activity against Gram positive bacteria, MICs were 0.1～6.2 μg/ml.更多还原