【摘要】 目的了解老年人糖尿病足坏疽（ＤＦ）的临床特征及其危险因素。方法对２２１例老年和１６３例老年前期ＤＦ的患病率、各种诱因的百分比、ＤＦ和非ＤＦ患者胫后感觉神经传导速度、双下肢动脉管径和血流量等检测结果进行分析。结果（１）老年和老年前期ＤＦ患者的患病率（４９．５％和２７．４％）明显高于青中年组（１１．０％）；自发性溃疡、水疱破裂、穿鞋不当摩擦伤为ＤＦ的常见诱因；湿性坏疽为ＤＦ的主要类型。（２）老年和老年前期ＤＦ患者因周围神经病变致传导速度检测不能引出波形者分别占９２％和８２％、周围血管病变致动脉狭窄和闭塞者分别占９２％和７８％，显著高于非ＤＦ组。结论老年人糖尿病易合并ＤＦ；周围神经病变和周围血管病变在ＤＦ的发生和发展中起重要作用。更多还原

【Abstract】 Objective To investigate the clinical characteristics and risk factors of diabetic foot (DF) in senile and presenile patients with diabetes mellitus (DM). Methods The prevalance rates of DF in 221 senile and 163 presenile patients and the percentage of precipitating factors for DF were analysed. Peripheral neuropathy(PN) and peripheral vascular disease (PVD) in senile and presenile patients with DF and without DF were compared through measuring their posterior tibialis sensory nerve conduction velocity and their internal diameter and volume flow of the arteries of the lower extremities. Results Prevalance rates of DF in senile and presenile (49 5% and 27 4%) were significantly higher than that in younger group(11 0%). Spontaneous ulcer, blister rupture, rubbing of foot were the most common precipitating factors for DF. Wet gangrene was a main type of DF.The analysis of risk factors showed that PN and PVD were more common and serious in patients with DF than in those without DF. Conclusions Senile and presenile patients with DM are more sufferd from DF; PN and PVD play important role in development of DF.更多还原