【摘要】 目的:研究紫外线照射充氧血液疗法（UBIO）对脑内血肿手术预后的影响,评价脑内血肿术后 UBIO 治疗的价值。方法:对脑内血肿术后患者35例除常规甘露醇治疗外,术后第1天始,用异体同型相合的静脉血200ml,紫外线照射并充氧后输注给患者,隔日1次,共3次。然后再用患者自体静脉血,同样方法紫外线照射充氧后回输,隔日1次,共2次。另35例作常规甘露醇等治疗。两组分别于术后第1,3,10天检测 SOD、TXB₂、PGI₂。结果:死亡率 UBIO 组为3%,常规组为43%,植物生存率为6%,P<0.01。U-BIO 组 TXB₂随治疗时间递减（P<0.001）,PGI₂增递（P<0.01）,TXB₂/PGI₂比值逐渐下降,SOD 递增（P<0.001）;常规组改变不恒定,可上升或降低,TXB₂/PGI₂比值无改变。结论:UBIO 治疗具有清除自由基,降低TXB₂/PGI₂比值,增加脑血流量,提高手术疗效的作用。更多还原

【Abstract】 Objective:To study the effect of ultraviolet blood irradiation and oxygenatio （UBIO） on intracerebral hematoma after surgery and its prognosis.Methods:35 cases with cerebral hematoma after surgery were treated with UBIO besides Mannitol therapy.After the first day of surgery,the hetero- transfusion 200ml radiated by UBIO were given,once every other day,for three times;then the auto- blood managed by UBIO was transfused,once every other day,for two times.Another 35 cases as a control group were only treated with Mannitol therapy.At the 1st,3rd and 10th day after UBIO,the levels of SOD,TXB₂ and PGI₂ in both groups were examined.Results:The mortality of the patients in UBIO group was obviously less than that of control group （3% vs.43%,P<0.01）.The level of TXB₂ and ratio of TXB ’PGI₂ were respectively decreased,and the value of PGI₂,SOD was increased gradully. However,the ges of these parameters in control group were not statistical significance.Conclusion: It suggests that the UBIO therapy is playing an important role in eliminating free radical,decreasing the ratio of TXB₂/PGI₂,increasing the cerebral bloodflow and operative outcome.更多还原