【摘要】 目的:探讨紫外线照射充氧自血回输（UBIO）对血清总胆固醇（Tch）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）及其亚组分Ⅱ（HDL₂-C）、亚组分Ⅲ（HDL₃-C）、低密度脂蛋白胆固醇（LDL-C）、载体蛋白（Apo）A₁、A₂、B₁₀₀、C₂、C₃的影响。方法:将冠心病高血脂患者分成两组,对照组27例,给予硝酸酯类和维生素类药物,UBIO 组32例加用光量子疗法。两组患者治疗期间停用其他影响血脂代谢的药物,1个疗程前后采外周静脉血,测上述各项指标。结果:UBIO 治疗后 Tch 降低（P<0.05）,TG、LDL-C、ApoB₁₀₀明显降低（P<001）,HDL₂-C 升高（P<0.01）,ApoA₁、ApoC₂均升高（P<0.05）;对照组上述指标均无显著变化（P>0.05）。结论:UBIO 有明显改善脂蛋白和载体蛋白代谢作用。更多还原

【Abstract】 Objective:In order to study the effect of ultraviolet blood irradiation and oxygenation（U- BIO） on blood lipid,lipoprotein and apolipoprotein in coronary heart diseasre （CHD）.Methods:59 CHD associatd with high-lipidemia patients were randomly divided into UBIO group（32 cases） and control group （27 cases）.The control group were only given the conventional lipid-reduing and vitamines drugs.The treatment group were treated with UBIO and above drugs.Before and after treatment,the levels of serum Tch,TG,HDL-C （including the HDL₂-C and HDL₃-c ）,LDL-C and apolipoprotein (in- cluding ApoA₁,ApoA₂,ApoB₁₀₀,ApoC₂,ApoC₃) all were measured and compared respectively.Results: After the treatment,level of Tch,TG,LDL-C and ApoB₁₀₀ decreased obviously （P<0.01）.The value of ApoA₁,ApoC₂ and HDL₂-C increased（P<0.05）.However,the above parameters of the control group were unchanged（P>0.05）.Conclusion:These data suggest that the UBIO therapy can improve the lipoprotein and apolipoprotein metabolism markedly.更多还原