【摘要】 为了观察洗必泰涂料的防龋效果，本研究以一种天然树胶山达脂为基质，配制１０％、２０％及４０％醋酸洗必泰涂料以及一种缓释剂，构成洗必泰涂料系统。体外测试其中洗必泰释放率，临床观察涂料系统对窝沟菌斑中变形链球菌及微生态系的影响。结果显示，洗必泰山达脂涂料能选择性抑制窝沟菌斑中变形链球菌的生长，而对血链球菌无影响。缓释剂起到缓释涂料中洗必泰的作用，延长了涂层与菌斑之间的相互作用时间。提示本涂料系统具有防龋功效，同时能维持口腔菌系平衡。更多还原

【Abstract】 A chlorhexidine varnish system and a controlled releasing varnish were prepared by the authors. The release rate of chlorhexidine in vitro and the effects on S. mutans and S. sanquis in vivo were determined. The results showed that the system could selectively inhibit the growth of S. mutans in fissure plaque and had no effect on S. sanquis. The period of interaction between the layer of varnish and plaque was prolonged by the control releasing reagent. The study suggests that the chlorhexidine varnish system is effective of anticaries and can maintain microflora balance in oral bacteria.更多还原