【摘要】 目的分析３ｃｍ以下食管癌病人的预后及与照射量之间的关系。材料与方法自１９７７年１月到１９８８年１２月共收治３ｃｍ以下的食管癌１９３例，男１１８例，女７５例。全部有病理证实，均为鳞癌。其中包括颈段癌３例，胸上段癌７８例，胸中段癌１０５例，胸下段癌７例。照射方法采用６０Ｃｏ外照射，常规３野，２００ｃＧｙ／次，５次／周，照射量４０８８～７３４５ｃＧｙ。结果１，３，５和８年生存率分别为７１．５％、４０．４％、３０．１％和１６．５％。以５０００～７０００ｃＧｙ组生存率最高，＞７０００ｃＧｙ组最差，且＜５０００ｃＧｙ组１和３年生存率明显高于＞７０００ｃＧｙ组，５和８年生存率无差别。结论食管癌病人的病变越短，生存率越高；病变部位与生存率的关系不大；最佳的照射量应为６０００ｃＧｙ左右／５周，对于３ｃｍ以下较早期的食管癌病人，放射治疗中不宜追求高剂量。更多还原

【Abstract】 Purpose To evaluate the correlation between prognosis and radiation doses of esophagus carcinoma with 3 cm or shorter than 3 cm lesions.Materials and Methods 193 patients with esophagus carcinoma ≤3 cm were treated by radiotherapy from January 1977 to December 1988,including male 118 cases and female 75 cases. All patients had pathological evidence of squamous carcinoma. There were 3 cases of neck segment ,78 cases of upper thoracic segment,105 cases of middle segment and 7 cases of lower segment.The conventional radiation method of three fields was adopted with cobalt-60,200 cGy per fraction and five fractions per week with the total doses of 4088 cGy to 7345 cGy.Results The survival rates of 1-,3-,5- and 8-year were 71.5%,40.4%,30% and 16.6% ,respectively. The best survival rate was the patients with doses of 5000 cGy to 7000 cGy. The survival rate of the patients with doses more than 7000 cGy was the worst. The 1-and 3-year survival rates of the patients with 5000cGy were better than that with doses more than 7000 cGy,but there were no significant difference between two groups in 5- and 8-year survival rates.Conclusion The shorter lesion of oesophageal carcinoma gives a better survival rate.The optimum radiation dose is 6000 cGy/6weeks.High dose is not necessary for the patients with earlier lesion of esophageal carcinoma.更多还原