【摘要】 采用彩色多普勒超声心动图（ＣＤＦＩ）对２１例合并有中、重度肺动脉高压（ＰＨ）的室间隔缺损（ＶＳＤ）患者的肺动脉收缩压（ＰＡＳＰ）进行检测，观察酚妥拉明用药后２ｍｉｎ、５ｍｉｎ、１０ｍｉｎ时的ＰＡＳＰ下降程度，并与手术对照。结果表明：ＰＡＳＰ下降以用药后５ｍｉｎ时最显著；中度ＰＨ患者较重度ｐＨ患者的ＰＡＳＰ下降明显，二者差异显著；ＰＡＳＰ较用药前下降４．７ｋＰａ以上者，术后心功能恢复快，下降在３．３～４．７ｋＰａ之间者，术后出现不同程度低心排等并发症，下降在３．３ｋＰａ以下者，死亡率较高。更多还原

【Abstract】 Pulmonary artery systolic pressure(PASP) was determined in 21 patients with middle and critical pulmonary hypertension(PH) associated with ventricular septal defect(VSD) by colour Doppler echocardiography; then we observed PASP change at time of 2’, 5’, 10’ after intravenous Regitine and in comparison with clinical operation treatment result. Study result as following fact: 1. PASP descensus was the most significant at 5’ after injecting Regitine. 2. patients’ PASP descensus degress with middle PH was more significant than that of critical PH. 3. resulte compared by statistical analysis were signigicant. 4. after infecting Regitine, if patients’ PASP descendens degress was larger than 4.7 kPa then operation was safety: if patients’ PASP descendens degress was from 3.3 kPa to 4.7 kPa then patients’ symptom appear low cardiac output syndrome of different degress operation; if patients’ PASP descendens degree was lower then 3.3 kPa then mortality was very high.更多还原