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检测胸水碱性蛋白、癌胚抗原和唾液酸监测临床治疗

Surveillance of Lung Cancer Progress by Determination of TBP,CEA and TSA in Pleural Effusion

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【作者】 符淑媛; 许德顺;

【Author】 Fu Shu-Yuan; Xu De-Shun (Oncological Department, Laboratory Center,The First Hospital of Jinzhou Medical College, Jinzhou )

【机构】 锦州医学院附属第一医院肿瘤科!辽宁省锦州市; 121001; 锦州医学院附属第一医院检验中心!辽宁省锦州市;

【摘要】 以联合检测晚期肺癌明水中TBP、CEA和TSA变化对临床治疗进行动态观察,结果62例病人有85.48%的TBP阳性率在出现明显疗效时降为32.26%;CEA和TSA水平也分别由治疗前的26.69μg/L、32.35μg/L和583.42mg/L、559.18mg/L降至6.21μg/L、8.44μg/L和349.64mg/L、396.29mg/L。因此认为三项指标的联合检测可以监测晚期肺癌的临床治疗,对经治医生适时地调整治疗方案有一定的指导作用。

【Abstract】 Sixty-two patients with advanced lung cancer were dynamlcally monitored by determination of tumor basic proteln (TBP), carcinoembryonlc antigen (CEA) and total sialic acid (TSA ) in pleural effusion of the patients. The results showed that the poslt1ve rate of TBP of all the patients reduced from 85. 48 %to 32. 26 % when prominent therapeutic effect was achieved. The levels of CEA and TSA markedly lowered after treatment. The study suggests that comblned determination of TBP, CEA and TSA can he used to monitor the therapeutic effects of advanced lung cancer.

【关键词】 胸水; TBP; CEA; TSA; 治疗监测;
【Key words】 Pleural effuslon Therapeutic effect TBP CEA TSA;
  • 【文献出处】 中国肿瘤临床 ,CHINESE JOURNAL OF CLINICAL ONCOLOGY , 编辑部邮箱 ,1997年12期
  • 【分类号】R730.5
  • 【被引频次】1
  • 【下载频次】15
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