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肝癌病人乙肝病毒活动状态及对外科干预的反应

The activity and reactions to the surgical intervention of hepatitis B virus in patients with hepatic cancer.

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【作者】 陈涛区庆嘉陈积圣邓庆丽张复春

【Author】 Chen Tao,Ou Qingjia,Chen Jisheng,et al.Department of Surgery,Memorial Hostpital,Sun Yatsen Memorial University of Medical Sciences,Guangzhou 510120

【机构】 中山医科大学附属孙逸仙纪念医院外科

【摘要】 对收治的97例肝癌病人(其中31例经手术治疗)采用定性PCR方法,并进一步采用定量PCR方法对14例乙肝阳性肝癌病人外科处理前后配对,研究了病毒活动状态及外科干预对病毒活动变化的影响。结果显示:肝癌阶段乙肝病毒仍然在一大部分病人体内进行着活跃的复制活动;外科干预更加激发乙肝病毒的复制过程。建议在肝癌外科干预的同时应当防范乙肝的活动。

【Abstract】 The correlation between hepatitis B virus(HBV)and hepatocellular carcinoma(HCC)has been confirmed by WHO since 1983.The viewpoint on the hepatitis B virus activity status is controversial after HCC established in patients and the effect surgical interventions does on hepatitis virus in this stage is unclear.We investigated 111 HCC patients with or without positive HBV markers the status of HBV activity by using PCR methods.The results show that replication process of hepatitis B virus is still strongly continuing in some patients and surgical interventions may result in promoting the process of virus replication.It is Suggested that we should pay more attention to the virus as well as to HCC in clinical practice.

  • 【文献出处】 中国实用外科杂志 ,CHINESE JOURNAL OF PRACTICAL SURGERY , 编辑部邮箱 ,1997年10期
  • 【分类号】R512.62
  • 【被引频次】23
  • 【下载频次】101
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