【摘要】 通过测定子宫内膜异位症患者细胞免疫功能以探讨其发病因素。采用单克隆抗体（ＣＤ３、ＣＤ４、ＣＤ８、ＣＤ５６）对２０例子宫内膜异位症患者，２０例子宫肌瘤患者，２０例正常妇女外周血Ｔ淋巴细胞亚群进行检测。结果：与正常妇女比较，内异症组Ｔ３、Ｔ４、Ｔ４／Ｔ８明显下降，有显著差异（Ｐ＜０．０１）；Ｔ８稍高（Ｐ＞０．０５）。与肌瘤组比较，内异症组Ｔ４、Ｔ８稍低，Ｔ３相近，Ｔ４／Ｔ８稍高，无显著差异（Ｐ＞０．０５）。肌瘤组与正常妇女比较，Ｔ３、Ｔ４／Ｔ８明显下降（Ｐ＜０．０１），Ｔ４稍下降（Ｐ＞０．０５），Ｔ８明显上升（Ｐ＜０．０５）。三组间ＮＫ细胞值为肌瘤组＞内异症组＞正常组，无显著差异（Ｐ＞０．０５）。提示：内异症患者细胞免疫功能低下，与子宫肌瘤患者相近。细胞免疫功能失调可能为其发病因素之一。更多还原

【Abstract】 bjective:To investigate the relationship between the cellular immunity function and the endometriosis.Methods:T-lymphocyte subsets were deter mined by the monoclonal antibodies(CD3,CD4,CD8,CD56)in 20 patients with endometriosis,20 patients with myoma of uterus and 20 normal women.Results:The percentage of T3/T4 and the ration of T4/T8 of patients with endometriosis were significantly lower than those of normal women(P<0.01).The percentage of T8 was not significantly increased (P>0.05).T4,T8 in endometriosis were lower than those in myoma of uterus T3 was the same in both group,T4/T8 was slightly higher,T3,T4/T8 in myoma of uterus were signifieantly lower than those in normal women(P<0.01).T4 was lower(P>0.05),T8 was significantly higher(P<0.05).The percentage of NK cell was that of myoma of uterus>endometriosis>normal women,but the difference was not significant(P>0.05).Conclusions:Cellular immunity function in patients with endometriosis is decreased. \ \更多还原