【摘要】 对１１６例妊高征患者同时检测血液流变性、血管紧张素Ⅱ（ａｎｇｉｏｔｏｎｉｍⅡ，ＡⅡ）、醛固酮（ａｌ－ｄｏｓｔｅｒｏｍｅ，ＡＬＤ）及血管内皮素（ｅｎｄｏｔｈｅｌｉｎ，ＥＴ），并与１００例正常孕晚期妇女作对照。结果提示：在妊高征患者中存在着三种不同情况：①血管紧张素Ⅱ增高；②醛固酮增高；③血管紧张素Ⅱ、醛固酮正常。应用无创性心血管血流参数检测见不同类型妊高征其血液动力学有着不同的改变。临床上根据监测指标作妊高征分型。采用不同治疗方法，高ＡⅡ型妊高征常有血液浓缩、低血容量，表现为低排高阻，可采用解痉、扩容治疗。醛固酮增高型妊高征呈低血粘度，常伴有血容量增加，心排出量增加，治疗以解痉、适当利尿，不需采用扩容治疗。更多还原

【Abstract】 Objective:To determine the relationship between the reninhypertension-aldosterone-prostaglandin system and viscosity hemorrheology in different types of PIH.Design:116 cases with PIH and 100 normal women were simultaneously analyzed about their viscosity hemorrheology,angiotonin,aldosterone and endothelin.Results:Our results suggested that there were 3 types of the patients with PIH:①Patients with high level of angiotonin Ⅱ(A Ⅱ),②Patients with high level of aldosterone.③Patients with normal level of A Ⅱand aldosterone.There was significant difference by comparing with the common pregnant women (P<0.01).Conclusion:That the different therapeutic method should be given to different patient with different type of PIH can get better treating result. \ \更多还原