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我国1996年急性弛缓性麻痹病例流行病学分析

AN EPIDEMIOLOGICAL ANALYSIS ON ACUTE FLACCID PARALYSIS(AFP) IN 1996,CHINA

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【作者】 李全乐张荣珍曹雷徐涛张兰香张兴录王克安

【Author】 Li Quanle Zhang Rongzhen Cao Lei Xu Tao Zhang Lanxiang Zhang Xinglu Wang Kean (National Technical Guiding Center of EPI,CAPM,Beijing,100050)

【机构】 中国预防医学科学院全国计划免疫技术指导中心

【摘要】 我国1996年急性弛缓性麻痹(AFP)病例监测工作进展显著,以省为单位各项监测指标已接近或达到了世界卫生组织(WHO)所提出的质量要求。我国1996年未发现本土脊髓灰质炎(脊灰)野病毒病例,仅在云南省与缅甸接壤地带发现3例输入性脊灰野病毒病例(Ⅰ型1例,Ⅲ型2例)。全国仍有554个县(区、市、旗,下同)连续4年未报告AFP病例,占全国县数的194%,主要分布于我国的东北、西北和西南地区。1993年以来,我国AFP病例主要分布于小年龄组,其中以脊灰和非脊灰肠道病毒感染病例尤为显著,5岁以下病例数分别占872%和861%。脊灰与脊灰排除病例的“零剂次”服苗率分别为424%和171%,≥3次服苗率分别为286%和635%,两者差异显著。我国AFP病例均以肢体麻痹为主,脊灰和非脊灰AFP病例肢体麻痹者分别占970%和989%,且均以下肢麻痹为主,其中脊灰病例的残留麻痹率为76%,显著的高于其他AFP病例。

【Abstract】 In 1996,China has achieved significant progress towards Acute Flaccid Paralysis (AFP) surveillance The quality control indicators for AFP surveillance by provinces have been so close or some even above the targets recommended by WHO By the end of 1996,no indigenous wild poliovirus was detected in China How ever,in Yunnan Province,3 imported laboratory-confirmed wild poliovirus cases (1 type Ⅰ,2 type Ⅲ) from Myanmar were reported In addition, from 1992 to 1996,the number of poliomyelitis cases reported from the Western Pacific Region (WPR) of the World Health Organization (WHO) and the global scale decreased dramatically In WPR there were 57% of polio cases from China, and in global there were 6 1% of polio cases from WPR But there were 544 counties for 4 years still with AFP case under reporting (silent areas) of which mainly distributed in the northeast, northwest and westsouth of China Since 1993, most of AFP cases reported were from very young children, especially for AFP cases related with polio and NPEV,which were 87% and 86% in children under 5 years old The vaccination rate of OPV "zero-dose" in clinically confirmed polio cases and discarded polio cases were 42 4% and 17 1% respectively, and the rate of OPV ≥3 doses inthose cases were 28 6% and 63 5% respectively,the difference between the two catgories waws significant Most of the paralyzed AFP cases involved with limbs ,in clinically confirmed polio cased and non polio AFP cases were about 97% and 98% respeclively chiefly attacked lower limbs The rate of residual paralysis in polio cases was 76%,that were sigficantly higher than that in other kinds of AFP cases

  • 【文献出处】 中国计划免疫 ,CHINESE JOURNAL OF VACCINES AND IMMUNIZATION , 编辑部邮箱 ,1997年06期
  • 【分类号】R512.4
  • 【被引频次】7
  • 【下载频次】34
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