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高血压患者脂质过氧化物及白细胞介素Ⅱ的相关性
Correlation of Lipid Peroxidation Product and Interleukin 2 in Patients with Essential Hypertension
【摘要】 目的探讨脂质过氧化物(MDA)及白细胞介素Ⅱ(IL-2)。方法用硫代巴比妥酸微量法及双抗夹心法测定46例高血压患者及20例健康的MDA和IL-2。结果高血压患者MDA明显高于健康对照组(P<0.05)而高血压患者IL-2明显低于对照组(r=-0.732,P<0.05)。结论高血压患者存在MDA和IL-2异常,IL-2与MDA有内在联系,氧自由基(OFR)损伤淋巴细胞可能是导致IL-2异常的原因之一。
【Abstract】 Aim\ To explore correlation and founction of interleukin 2(IL 2) and malondialdehyde(MDA) in thirty three patients with essential hypertension(EH) and compared with normal control subjects.\ Methods\ IL 2 and MDA were measured by enzymelinked immunoassay and thiobarbiturates method.\ Results\ MDA was sigmificantly higher and IL 2 was significantly lower(P<0.05) in EH than normal subjects.Linear correlation between IL 2 and MDA was r=-0.732,P<0.05.\ Conclusion\ MDA had negative correlation with IL 2,lower of IL 2 may be ascribed to the more production of oxidative free radical.
- 【文献出处】 高血压杂志 ,CHINESE JOURNAL OF HYPERTENSION , 编辑部邮箱 ,1997年03期
- 【分类号】R544.1
- 【被引频次】1
- 【下载频次】23