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高血压患者的血压昼夜节律变化与靶器官损害

The Circadian Change of Blood Pressure and Target Organ Damage in Hypertensive Patients

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【作者】 孙刚王峰丁燕程俞澜吴国霞王绍贞

【Author】 Sun Gang, Wang Feng, Ding Yancheng, Yu Lan, Wu Guoxia, Wang Shaozhen (The Hypertension Research Unit, Affiliated Second Hospital of Baotou Medical College)

【机构】 包头医学院第二附属医院高血压研究室

【摘要】 目的研究原发性高血压(EH)患者血压昼夜节律改变与高血压病期及严重程度的关系。方法应用无创动态血压监测系统记录24h血压并分析正常人组(52例)、高血压Ⅰ期(48例)、Ⅱ期(85例)、Ⅲ期(32例)患者白昼与夜间的血压变化。结果I~Ⅲ期患者夜间收缩压(SBP),舒张压(DBP)下降率分别为18%,15%;8%,7%;1%,2%;昼夜节律紊乱Ⅰ期6%,Ⅱ期36%,Ⅲ期84%。Ⅰ期夜间SBP下降率高于正常人组(P<0.05)。结论夜间血压下降率可以做为临床上高血压程度及靶器官受损评估的一项指标。

【Abstract】 Aim \ To study the relationship between circadian blood pressure and target organs damages.\ Methods\ 52 normotensive and 165 essential hyperensive(EH) subjects in different stages were investigated with noninvasive ambulant blood pressure mornitoring(ABPM).\ Results\ That in night time the decline rate of systolic blood pressure(SBP) and diastolic blood pressure(DBP) were 18% and 15% in stage Ⅰ,8% and 7% in stage Ⅱ,1% and 2% in stage Ⅲ respectively. Day and night rhythmic disorder occur in 6% in Ⅰ,36% in Ⅱ,84% in Ⅲ.\ Conclusion\ This study comfirms that non dipper phenomena may be considered as a index for evaluating the severity of EH and target organs involvement.

  • 【文献出处】 高血压杂志 ,CHINESE JOURNAL OF HYPERTENSION , 编辑部邮箱 ,1997年03期
  • 【分类号】R544.1
  • 【被引频次】47
  • 【下载频次】110
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