【摘要】 目的探讨软组织肉瘤术后复发原因及治疗问题。方法回顾性分析了４２例软组织肉瘤术后复发的病例，分析了首次手术方式与复发时间的关系及综合治疗与单纯手术疗效间的差异。结果首次手术方式为肿瘤切除术者３１例，扩大切除术者１１例，半年内局部复发率前者显著高于后者（８０６％和２７３％，Ｐ＜００５）。４２例全部再次行扩大切除术，其中手术加放疗、化疗２９例，单纯手术１３例，３年的局部未复发率，前者较后者显著提高（８２８％和５３８％，Ｐ＜００５）。结论软组织肉瘤治疗的效果取决于首次治疗的正确性和彻底性。扩大手术辅以放疗、化疗可延缓局部复发时间。更多还原

【Abstract】 PURPOSE To study the causes of recurrence and methods of therapy.METHODS 42 cases of recurrent soft tissue sarcoma were analyzed retrospectively, as well as the relation between methods of primary surgery and multidisciplinary therapy.RESULTS In 31 cases the primary operation was tumor excision, while in 11 cases it was wide resection. At 6 months followup, the local recurrence rate of the first method was 80.6%, while in the latter it was 27.3%(P<0.05).These recurrent cases were reoperated, 29 cases received multidisciplinary therapy including surgery, chemotherapy and radiotherapy. The other 13 cases had surgery only. Followup at 3 years showed that local cure rate for the combined therapy cases was 82.8%, while for the surgery only cases it was 53.8%(P<005)CONCLUSIONS The results of therapy in soft tissue sarcomas depend on the correctness and thoroughness of the primary treatment. Multidisciplinary therapy can improve the local cure rate delay recurrence.更多还原