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地塞米松注入家兔眼前房的实验研究

An Experimental Study on Dexamethasone in Rabbit Anterior Chamber

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【作者】 陶黎明; 廖荣丰; 吴邦安; 陈逖;

【Author】 Tao Liming,Liao Rongfeng,Wu Bangan,et al.Department of Ophthalmology,the First Affiliated Medical University of Anhui.Hefei 230022

【机构】 安徽医科大学第一附属医院眼科;

【摘要】 目的实验观察地塞米松(dexamethasone,DXM)注入家兔眼前房的不良反应。方法将30只兔右眼前房注入DXM0.2ml(含0.2mg),左眼前房注入BSS液作对照,术后观察角膜及前房的反应。结果试验组的眼角膜及前房反应明显高于对照组。结论结合DXM的药剂学资料,认为使用不纯的DXM制剂作眼内注射是不安全的。

【Abstract】 ObjectiveTo determine whether intracameral injection of dexamethasone(DXM) may have a toxic effect.Methods0.2ml(contain 0.4mg) DXM was injected into the right anterior chambers of 30 rabbits.BSS solution as the control was injected into the left eyes.The reaction of the cornea and anterior chamber were investigated after operation.ResultsThe reactions of the cornea and anterior chamber in the test groups were more than those on the control groups.ConclusionBased on pharmaceatical data of DXM,it is suggested that intracameral injection of DXM is unsafe.

【关键词】 地塞米松; 前房;
【Key words】 examethasone; anterior; chamber;
  • 【文献出处】 眼科研究 ,CHINESE OPHTHALMIC RESEARCH , 编辑部邮箱 ,1997年02期
  • 【分类号】R-332
  • 【被引频次】2
  • 【下载频次】16
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