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一些新的磺胺衍生物的合成研究
Study on Synthesis of Some New Derivatives of Sulfanilamide Containing Tetracarbon Ring of Squaric Acid
【摘要】 众所周知,大多数磺胺用于治疗各种疾病,结构奇特的方酸具有特定的功能。我们成功地将磺胺结构单元引入方酸四碳环,制得14个新的含方酰基的磺胺衍生物,确证了结构。预期这类化合物有新的生物活性。
【Abstract】 It is well - known that most sulfanilamides are used for the treatment infective or other diseases,whereas function of tetracarbon ring of squaric acid which has special structure and property has been proved by a large number of related studies. We have successfully introduced structural unit of some sulfanilamide into the tetracarbon ring. 14 new derivatives of sulfanilamide were obtained and their structures were determined. It is expected that combining structural unit of sulfanilamide with tetracarbon ring might lead to new bioactive compounds.
【关键词】 磺胺;
方酰胺;
磺胺衍生物;
环丁烯二酮;
【Key words】 sulf anilamide; squaric acid amide; derivative of sulf anilamide; cyclobutenedione;
【Key words】 sulf anilamide; squaric acid amide; derivative of sulf anilamide; cyclobutenedione;
- 【文献出处】 有机化学 ,Chinese Journal of Organic Chemistry , 编辑部邮箱 ,1997年06期
- 【分类号】O623.7
- 【被引频次】3
- 【下载频次】169