【摘要】 本研究采用豚鼠股静脉内注射四碘四氯荧光素二钠，以波长为550±20nm绿色光束照射耳蜗的方法，诱导豚鼠耳蜗血管内发生光化学反应，造成豚鼠耳蜗微循环障碍的动物模型，以复合动作电位（CAP）振幅为指标，通过给豚鼠股静脉注射复方丹参注射液，观察丹参对造模豚鼠CAP的影响。结果：实验组与对照组比较，CAP振幅相对值明显提高（P＜0．001），提示丹参有改善造模豚鼠耳蜗微循环障碍的作用。并探讨其机理。更多还原

【Abstract】 In this study, after intravenous injection of Rose bengal, the lateral wall of the cocblea of guinea pigs was illuminated with green light (wavelength: 550±20nm),subsequent pbotochemcal reaction was occured and the animal model of cochlea microcirculatory disorders was made by this way. The CAP amplitude N1 was measured to observe the effect of the injectbo of Danshen on model guinea pigs. The result was showed that the relative value of CAP amplitude of vibration (measured CAP ampiitude/normal CPH amplitude x 100%) of Danshen group was increased obviously compared with control group (P<0.001).It is suggested tbat Danshen improtre the cochlea microcirculatory disorders of model guinea pigs, and its mechanism was also discussed.更多还原