节点文献
我国儿童大肠癌58例分析
An analysis of 58 cases of colorectal carcinoma in Chinese children
【摘要】 目的分析我国儿童大肠癌的临床及病理特点.方法收集1949年~1996年国内正式发表的儿童大肠癌病例进行回顾性分析.结果全部共58例,男46例,女12例;年龄7月龄~15岁.①儿童大肠癌在全部大肠癌中的比例约为041%~077%;②主要发生于右半结肠、横结肠及直肠,分别为431%和414%;③容易误诊,误诊率高达769%;④病理类型以粘液腺癌为主,占708%;⑤根治性切除的机会为655%,远较成人低;⑥预后差,2年生存率为548%,无5年生存者;⑦病因不明,与种族及家族倾向关系亦不清楚;⑧目前尚缺乏成熟的综合治疗措施与经验.结论中国儿童大肠癌有一定特点.
【Abstract】 AIM To analyse the clinical and pathological features of colorectal carcinoma in Chinese children. METHODS Reported cases from 1949 to 1996 of colorectal carcinoma in Chinese journals were collected and retrospectively reviewed. RESULTS There were 58 cases altogether; 46 were male, and 12 female with age range of 7 months to 15 years. ①Colorectal carcinoma in children accounts for about 0 41%~0 77% in the large bowel carcinomas; ②Main sites of tumor were in transverse or rightside colon and rectum (43 1% and 41 4% respectively); ③ High rate of misdiagnosis (76 9%); ④ The predominant pathological patterns were mucinoadenocarcinoma, nondifferential carcinoma and signet ring cell carcinoma, with higher malignancy; ⑤ The rate of radical resection was lower (65 5%) than that in adult; ⑥ With poor prognosis, the 2 year survival rate was 54 8%, no 5 year survivals; ⑦The etiology was not clear, and no combined effective methods and experience are available. CONCLUSION The colorectal carcinoma in Chinese children does have some characteristics.
【Key words】 colonic neoplasms/pathology; rectal neoplasms/pathology; adenocarcinoma, mucinous;
- 【文献出处】 新消化病学杂志 , 编辑部邮箱 ,1997年10期
- 【分类号】R735.34
- 【被引频次】4
- 【下载频次】65