【摘要】 目的探讨活检部位与Ｈｐ的检出率，观察内镜下喷洒美蓝治疗Ｈｐ的效果．方法选择内镜下诊断的慢性萎缩性胃炎或其它胃病伴有萎缩改变及肠上皮化生改变者２６８例．对其萎缩面的形态、肠上皮化生的特点进行分型．结果闭合型萎缩性胃炎以窦部Ｈｐ检出率高，而开放型以体部检出率高（Ｐ＜００１），肠上皮化生广泛的部位，Ｈｐ检出率低（Ｐ＜００１）．美蓝喷洒法与口服法比较具有相同治疗效果．结论内镜下取活检的部位及肠上皮化生的程度可影响Ｈｐ检出率．喷洒美蓝治疗Ｈｐ法，经济、效果好、副作用少．更多还原

【Abstract】 AIM To investigate the relationship between the site of biopsy and the Helicobacter pylori (Hp) positive rate, and study the effect of methylene blue for Hp. METHODS The Hp infections of 268 patients with atrophic or intestinal metaplasia were observed, and the shape and distribution of atrophic gastric mucosa was classified. RESULTS Hp positive rate is high in closed type of atrophic gastritis on antrum, while in open type is high on corpus(P<0 01). Hp positive rate is low in cases of extensive intestinal metaplasia (P<0 01). CONCLUSION The results showed that biopsy site and degree of intestinal metaplasia can influence Hp positive rate. The methylene blue spraying is economical and effective for Hp treatment and has few side effects.更多还原