【摘要】 对湖北汉川县中度流行区3个村3－70岁人群行IHA检测。对IHA阳性者调查IgE基线水平及有关影响因素。化疗后3－7个月测期终IgE水平。完成期终观察116人，其中化疗组85人，未化疗组31人；前者IgE阴转率78．57％（66／84），明显高于后者阴转率24．14％（7／29），IgE的GMT下降幅度亦明显高于后者。结果显示化疗是致IgE下降的主要因素。多因素Logistic回归分析发现，两组影响IgE动态变化的共同因素是嗜酸性粒细胞计数（EOSCUT）和疫水接触指数（WCI）。更多还原

【Abstract】 IHA test was conducted for 3-70 old years population residing in the moderate endemic aear of Schistosomiasis Japonica in Hanchuan County,Hubei Province Basic level of specific IgE antibody and the concerned factors affecting the IgE of the persons whose IHA was posi- tive were investigated A survey on observed-end-level of IgE was carried out from 3 - 7 months after chemotherapy with praziquantel Total 116 persons in this study were followed up,which included 85 to be as chemotherapy group,and 31 as nonchemotherapy group. The negative-turning rate of IgE antibody was 78. 57% in the former group but in the latter group was 24. 14% (P=0.0000),the GMT of IgE in chemothrapy group declined significat- ly. The results showed that the chemothrapy was a main factor for dropping of IgE antibody. Logistic regression analysis with multiple factors found that eosinophil cells count (EOSCUT) and water contact index (WCT) were two common factors for the two groups.更多还原