节点文献

铕苯丙氨酸配合物与DNA相互作用的循环伏安法和紫外光谱法研究

Study on Interaction between Eu Phenylanaline and DNA by Using of Cyclic Voltammetry and UV Spectroscopy

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 沈鹤柏蒯丽衡倪丽华李建粤章宗穰

【Author】 Shen Hebai, Kuai Liheng, Ni Lihua, Li Jianyue, Zhang Zongrang( Department of Chemistry and Department of Biology, Shanghai Teachers University, Shanghai 200234, China )

【机构】 上海师范大学化学系

【摘要】 运用循环伏安法和紫外光谱法研究了Eu(phe)3+3与DNA的相互作用。Eu(phe)3+3与DNA作用后,循环伏安曲线的峰电流密度减小,峰电位差稍有增加,扩散系数减小。紫外光谱的特征吸收峰呈明显的减色效应。这可能是Eu(phe)3+3与DNA因静电引力形成加合物以及Eu(phe)3+3有很强的遮蔽负电荷的作用,促使碱基面与碱基面的进一步堆积(stacking)所致。

【Abstract】 The interaction between DNA and the Eu(phe) 3+ 3 complex ion was studied by using of cyclic voltammetry and differential UV spectroscopy. The results depicted an obvious decrease of peak current in CV plot after the interaction between two studied species. The observed peak potential separation was increased, but the diffusion coefficient of Eu complex ion was decreased. Hypochromicity was observed at 226 nm and 258 nm after the predicted interaction of them. Preliminary interpretation is proposed for discussion.

【基金】 上海市教委重点学科基金
  • 【文献出处】 中国稀土学报 ,JOURNAL OF THE CHINESE RARE EARTH SOCIETY , 编辑部邮箱 ,1997年02期
  • 【分类号】O646
  • 【被引频次】28
  • 【下载频次】310
节点文献中: 

本文链接的文献网络图示:

本文的引文网络