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原发性肝癌高发现场高危人群筛检研究

Study on Screening Population with High Risk of PHC in High Incidence Field

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【作者】 薛常镐钟文玲陈铁晖孙昌盛郑英杰郑君玉康天尝洪作艺陈晓鹭

【Author】 Xue Changhao;Zhong Wenlin; Chen Tiehui, et al. (Fujian Centers for Disease Controi, Fuzhou 350001)

【机构】 福建省卫生防疫站!福州350001福建医科大学!福州360004上海医科大学!上海200032同安县卫生防疫站!同安361100同安县肝癌防治研究室!同安

【摘要】 目的:探讨肝癌高发现场发现早期肝癌的有效方法,查明HBV感染与肝癌的关系。方法:本文应用ELISA方法筛检同安县肝癌高发人群,并对筛检后的HBsAg、AFP阳性人群进行前瞻观察。结果:检出原发性肝癌7例,HBsAg阳性肝癌检出率是HBsAg阴性肝癌检出率的11.6倍(P<0.01);前瞻观察结果,发现肝癌20例,HBsAs阳性者肝癌发生率(210、93/10万)是HBsAs阴性着肝癌发生率(3452/10万)的6.11倍(P<0.01)。结论:表明农村肝癌高发现杨高危人群筛检有一定应用价值,有叶能进一步揭示HBV感染与肝癌的病因学关系。

【Abstract】 Purpose: To study the means of screening in Population with high risk of PHC and to investigate the correlation between HBV infection and PHC. Method: Mass screen was undertaken to look for Positive HBsAg and AFP by means of ELISA. Prespective observation was carried out to the population of positive HBsAg and AFP. Results: Seven cases of PHC were detected. PHC detected rate in population With HBsAg positive was 11. 6 titnes higher than that in HBsAg negative. From prespective observation, 20 cases PHC were found. The incidence of HBsAg Positive population was 210. 93/103, it was 6. 11 times of the HBsAg negatlve population (P<0.01). Conclusion: It is value to screen the population with high risk of PHC in contryside and it probably further reveals the relatboship between HBV infection and etiology of PHC.

【基金】 福建省“八五”重点科技攻关项目
  • 【文献出处】 浙江肿瘤 ,Zhejiang Cancer Journal , 编辑部邮箱 ,1997年02期
  • 【分类号】R735.7
  • 【下载频次】62
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