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原发性肝癌高发现场高危人群筛检研究
Study on Screening Population with High Risk of PHC in High Incidence Field
【摘要】 目的:探讨肝癌高发现场发现早期肝癌的有效方法,查明HBV感染与肝癌的关系。方法:本文应用ELISA方法筛检同安县肝癌高发人群,并对筛检后的HBsAg、AFP阳性人群进行前瞻观察。结果:检出原发性肝癌7例,HBsAg阳性肝癌检出率是HBsAg阴性肝癌检出率的11.6倍(P<0.01);前瞻观察结果,发现肝癌20例,HBsAs阳性者肝癌发生率(210、93/10万)是HBsAs阴性着肝癌发生率(3452/10万)的6.11倍(P<0.01)。结论:表明农村肝癌高发现杨高危人群筛检有一定应用价值,有叶能进一步揭示HBV感染与肝癌的病因学关系。
【Abstract】 Purpose: To study the means of screening in Population with high risk of PHC and to investigate the correlation between HBV infection and PHC. Method: Mass screen was undertaken to look for Positive HBsAg and AFP by means of ELISA. Prespective observation was carried out to the population of positive HBsAg and AFP. Results: Seven cases of PHC were detected. PHC detected rate in population With HBsAg positive was 11. 6 titnes higher than that in HBsAg negative. From prespective observation, 20 cases PHC were found. The incidence of HBsAg Positive population was 210. 93/103, it was 6. 11 times of the HBsAg negatlve population (P<0.01). Conclusion: It is value to screen the population with high risk of PHC in contryside and it probably further reveals the relatboship between HBV infection and etiology of PHC.
【Key words】 Primary hepatocellular carcinoma; Population with high risk; Screening;
- 【文献出处】 浙江肿瘤 ,Zhejiang Cancer Journal , 编辑部邮箱 ,1997年02期
- 【分类号】R735.7
- 【下载频次】62