【摘要】 本文应用２４ｈ动态心电图对健康人（对照组）和冠心病心绞痛、心肌梗死患者进行心率变异性研究。结果发现：心绞痛组和前壁心梗组的正常ＲＲ间期总体标准差（ＳＤＮＮ）、每连续５ｍｉｎ时段正常ＲＲ间期均值的标准差（ＳＤＡＮＮ）及其平均值（ＳＤＮＮｉｎｄｅｘ）、心率总功率（ＴＰ）、极低频功率（ＶＬＦ）、低频功率（ＬＦ）和高频功率（ＨＦ）等均低于对照组（均Ｐ＜０．０１）；下壁心梗组的ＳＤＮＮ，ＳＤＮＮｉｎｄｅｘ和ＬＦ低于对照组（均Ｐ＜０．０５）；前壁心梗组的ＳＤＮＮ，ＳＤＡＮＮ和ＬＦ低于心绞痛组（均Ｐ＜０．０５）。心率变异诊断冠心病的阳性标准取低于对照组上述任一项指标９５％区间下限值，则其特异性为９３．９％，心绞痛组敏感性为５１．２％，心梗组为７１．４％。提示心率变异下降对冠心病的诊断有一定的参考价值。更多还原

【Abstract】 The time domain and frequency domain of heart rate variability (HRV) were studied in patients with coronary heart disease and normal controls from 24 hour electrocardiography. The results showed that SDNN,SDANN, SDNNindex, TP, VLF, LF and HF were markedly decreased in 41 patients with angina pectoris (Anginas) and 17 patients with acute anterior myocardial infarction (AAMIS) compared with 33 controls(all P<0.01). SDNN, SDNNindex and LF were reduced in acute inferior myocardial infarction (AIMIS) compared withcontrols (all P<0.05). SDNN,SDANN and LF were reduced in AAMIS compared with Anginas. The abnormality of HRV were diagnosed if the value of any index was lower than the threshold (1.96s of controls). The specificity of the diagnosis standard was 93.9%,its sensitivity was 51.2% in Anginas,71.4% in AMIS. These results indicate that the impairment of autonomic nervous system function are associated with degree of myocardial injury and HRV might be taken as a diagnostic indicator.更多还原