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峨眉茶抗突变试验

THE STUDY OF ANTIMUTAGENESIS OF EMEI TEA

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【作者】 曾令福; 罗素琼; 劳春梅;

【Author】 Zeng Lingfu,et alSchool of Public Health,West China Univercity of Medical Sciences,Chengdu 610041

【机构】 华西医科大学公共卫生学院;

【摘要】 峨嵋茶为四川峨嵋山生长的一种优质绿茶。本文采用小鼠微核试验、小鼠精子畸变试验、姊妹染色单体互换试验对峨嵋茶及其茶多酚的抗突变作用进行研究。结果:峨嵋菜水浸液浓度为1.25%—2.5%时,对环磷酰胺诱发小鼠骨髓嗜多染红细胞微核抑制率为41%—45%、小鼠精子畸变抑制率为73.5%—82.3%、每毫升培养液含峨嵋菜水浸液20、200mg、峨嵋茶茶多酚2、20、200mg时,对丝裂霉素C诱发人外周血淋巴细胞姊妹染色单体互换抑制率分别为37.5%—49.59%;36.12%—69.81%。表明:峨嵋茶及其茶多酚对环磷酰胺诱发小鼠骨髓微核出现率、小鼠精子畸变率、丝裂霉素C诱发人外周血淋巴细胞姊妹染色单体互换率均有较好抑制作用。

【Abstract】 Emei tea is a kind of good quality green tea growing at Emei mountain In this paper we uesed the micronuclei analysis、sperm aberration test of mouse and SCE test of peripheral blood lymphocytes of human to sdudy the antimutagenesis of Emei tea and its green tea polyphenol (GTP), the results showed that when the concenration of water extractive of Emei tea was 125%-25%,the inhibitory rate on micronuclei and sperm abrration of mouse induced by CP was 41%-45%,735%-823%,respectively;when the concentration of water extractive of tea and its GTP in culture medium was 20、200mg/ml,and 2、20、200mg/ml,the inhibitory rate on SCE induced by MMC was 3753%-4959% and 3612%-6981% It is showed that Emei tea and GTP can inhibit the mutagenesis of CP and MMC efficiently

【关键词】 峨嵋菜; 菜多酚; 抗突变;
【Key words】 antimutagenesis Emei tea GTP;
  • 【文献出处】 现代预防医学 ,MODERN PREVENTIVE MEDICINE , 编辑部邮箱 ,1997年03期
  • 【分类号】R73-3;Q343
  • 【被引频次】3
  • 【下载频次】28
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