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峨眉茶抗突变试验
THE STUDY OF ANTIMUTAGENESIS OF EMEI TEA
【摘要】 峨嵋茶为四川峨嵋山生长的一种优质绿茶。本文采用小鼠微核试验、小鼠精子畸变试验、姊妹染色单体互换试验对峨嵋茶及其茶多酚的抗突变作用进行研究。结果:峨嵋菜水浸液浓度为1.25%—2.5%时,对环磷酰胺诱发小鼠骨髓嗜多染红细胞微核抑制率为41%—45%、小鼠精子畸变抑制率为73.5%—82.3%、每毫升培养液含峨嵋菜水浸液20、200mg、峨嵋茶茶多酚2、20、200mg时,对丝裂霉素C诱发人外周血淋巴细胞姊妹染色单体互换抑制率分别为37.5%—49.59%;36.12%—69.81%。表明:峨嵋茶及其茶多酚对环磷酰胺诱发小鼠骨髓微核出现率、小鼠精子畸变率、丝裂霉素C诱发人外周血淋巴细胞姊妹染色单体互换率均有较好抑制作用。
【Abstract】 Emei tea is a kind of good quality green tea growing at Emei mountain In this paper we uesed the micronuclei analysis、sperm aberration test of mouse and SCE test of peripheral blood lymphocytes of human to sdudy the antimutagenesis of Emei tea and its green tea polyphenol (GTP), the results showed that when the concenration of water extractive of Emei tea was 125%-25%,the inhibitory rate on micronuclei and sperm abrration of mouse induced by CP was 41%-45%,735%-823%,respectively;when the concentration of water extractive of tea and its GTP in culture medium was 20、200mg/ml,and 2、20、200mg/ml,the inhibitory rate on SCE induced by MMC was 3753%-4959% and 3612%-6981% It is showed that Emei tea and GTP can inhibit the mutagenesis of CP and MMC efficiently
- 【文献出处】 现代预防医学 ,MODERN PREVENTIVE MEDICINE , 编辑部邮箱 ,1997年03期
- 【分类号】R73-3;Q343
- 【被引频次】3
- 【下载频次】28