【摘要】 本文对大白鼠下齿槽动脉的正常组织结构及在下颌骨内的走行分布,通过动脉灌注及三重染色等研究手段,进行了光镜和电镜观察和测量,同时对老龄大白鼠下齿槽动脉的增龄性改变进行了组织学研究.观察到增龄老化的下齿槽动脉血管壁,有明显的生理性硬化和病理性栓塞.这一组织学改变与人类动脉硬化的生理和病理改变相类似,对进一步研究人类下齿槽动脉增龄性改变对下颌骨血运的影响具有重要的意义.更多还原

【Abstract】 The inferior alveolar artery (IAAJ in the mandibular canal of male rats varying from 7 weeks to 2 years was examined arteriographically and histologically. Developmental changes in the IAA were noted in the period of nursing or feeding. At the age of 7 weeks, the structure of the vessel wall of the IAA was the muscular type, showing the typical three layers of lamina intima, lamina media and lamina adventitia, as visualized by trichrome staining with malachite green, toluidine blue and basic fuchsin. Histological changes in the IAA were found in the endothelial cells, the internal elastic limina, and the smooth muscle cells untill the age of 7 weeks. At the age of 2 years, in the vessel wall of IAA, the arterosclerosis and arterial embolism were observed. These pathologic histological changes are the same as the physiological and pathologic changes of the human arterosclerosis.更多还原